Prolotherapy (polo = proliferative) has been around officially since the 1950s, with variants of the technique pre-dating that. With the primary component of the solution injected being dextrose (a form of sugar), the therapy was not a subject of extensive drug trials and lost favor to more eloquent or extensively studied drug approaches.
In part due to its undeniable effectiveness, along with its high level of safety as an injected therapy, more recent research has helped proven its effectiveness, including Level I studies (the top tier and most conclusive from a research standpoint). A landmark study proved undeniable effectiveness for knee arthritis, with several other smaller studies proving its use in other conditions, particularly those involving ligament damage or laxity. Physicians that are well trained in prolotherapy can effectively treat most chronic joint conditions where ligament damage is present. Prolotherapy can stimulate an immune response similar to PRP, but recent research also show dextrose has an effect on nerve pain, which interestingly also is directly involved with ligamentous injury.
Chronic sprains, strains, tendonosis (Tennis elbow, plantar fasciitis, patellar tendonitis, achilles tendonitis, etc)
Rotator cuff injuries
Chronic shoulder subluxation
Ligament laxity and joint instability, including Ehlers-Danlos spectrum
Chronic pain from motor vehicle accidents, whiplash
Spine related pain (cervical, thoracic, lumbar, sacroiliac)
Rib, costovertebral pain
"You'll recall the last shoulder prolo treatment you gave me included breaking up that calcium deposit. Whether it worked or not I don't know but after about a week or so I started to have better mobility in the shoulder. I am back at a gym about five days a week doing core body exercises (and not abusing my shoulders or elbows.) The regular exercise has no doubt also helped. Anyway, I'm now flying on my own and not thinking very much about my shoulders or elbows! Yippee! THANKS A MILLION for your kindness and great prolo treatments and saving me from the scalpel!"
- D.P. (tennis elbow, shoulder calcific tendinosis)
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